Disease-gene associations mined from literature

Literature associating RIC8B and amelogenesis imperfecta type 3

RIC8B [ENSP00000376583]

RIC8 guanine nucleotide exchange factor B; Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction; Belongs to the synembryn family.

Synonyms:  RIC8B,  RIC8Bp,  hRIC8B,  A0A024RBG9,  B7WPL0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM