Disease-gene associations mined from literature

Literature associating CD79B and lambda 5 deficiency

CD79B [ENSP00000376544]

B-cell antigen receptor complex-associated protein beta chain; Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.

Synonyms:  CD79B,  CD79Bp,  hCD79B,  P40259,  P40259p ...

Linkouts:  STRING  Pharos  UniProt  OMIM