Literature associating CIT and primary autosomal recessive microcephaly
Citron rho-interacting serine/threonine kinase; Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.
Synonyms: CIT, F5H4K4, H0YGG8, O14578, CRIK ...