Disease-gene associations mined from literature

Literature associating SP140 and primary biliary cholangitis

SP140 [ENSP00000375899]

Lymphoid-restricted homolog of Sp100; Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection. May play a role in chromatin-mediated regulation of gene expression although it does not bind to histone H3 tails; Bromodomain containing

Synonyms:  SP140,  LOC101928789,  SP140p,  hSP140,  E7ESH9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM