Literature associating CARD8 and Masters-Allen syndrome
Tumor up-regulated CARD-containing antagonist of CASP9; Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases; Caspase recruitment domain containing
Synonyms: CARD8, CARD8p, hCARD8, CARD8-001, CARD8-002 ...