Disease-gene associations mined from literature

Literature associating CCDC88C and cerebral degeneration

CCDC88C [ENSP00000374507]

Dvl-associating protein with a high frequency of leucine residues; Negative regulator of the canonical Wnt signaling pathway, acting downstream of DVL to inhibit CTNNB1/Beta-catenin stabilization (By similarity). May also activate the JNK signaling pathway; Belongs to the CCDC88 family.

Synonyms:  CCDC88C,  CCDC88Cp,  hCCDC88C,  B4DZB8,  CCDC88C-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM