DISEASES

Disease-gene associations mined from literature

Literature associating GARS and hyperekplexia

GARS [ENSP00000373918]

Diadenosine tetraphosphate synthetase; Catalyzes the ligation of glycine to the 3'-end of its cognate tRNA. Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs; Belongs to the class-II aminoacyl-tRNA synthetase family.

Synonyms:  GARS,  F8WCK4,  GARS-001,  GARS-002,  GARS-003 ...

Linkouts:  STRING  Pharos  UniProt  OMIM