Disease-gene associations mined from literature

Literature associating DNM2 and Charcot-Marie-Tooth disease dominant intermediate A

DNM2 [ENSP00000373905]

Dynamin 2; Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis. Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane (By similarity); Pleckstrin homology domain containing

Synonyms:  DNM2,  DNM2p,  hDNM2,  A0A024R7C9,  DNM2-001 ...

Linkouts:  STRING  Pharos  UniProt