DISEASES

Disease-gene associations mined from literature

Literature associating DENND5B and lissencephaly 8

DENND5B [ENSP00000373734]

DENN domain-containing protein 5B; Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form; DENN/MADD domain containing

Synonyms:  DENND5B,  DENND5Bp,  hDENND5B,  F5H4A0,  G3V1S3 ...

Linkouts:  STRING  Pharos  UniProt