DISEASES

Disease-gene associations mined from literature

Literature associating TYRP1 and cataract 9 multiple types

TYRP1 [ENSP00000373570]

5,6-dihydroxyindole-2-carboxylic acid oxidase; Catalyzes the oxidation of 5,6-dihydroxyindole-2- carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin (By similarity).

Synonyms:  TYRP1,  TYRP1p,  hTYRP1,  B4DNE6,  C9JZ52 ...

Linkouts:  STRING  Pharos  UniProt  OMIM