DISEASES

Disease-gene associations mined from literature

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Literature associating SRGAP3 and lissencephaly 5

SRGAP3 [ENSP00000373347]

WAVE-associated Rac GTPase-activating protein; GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons; F-BAR domain containing

Synonyms:  SRGAP3,  SRGAP3p,  hSRGAP3,  O43295,  ARHGAP14 ...

Linkouts:  STRING  Pharos  UniProt  OMIM

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.