DISEASES

Disease-gene associations mined from literature

Literature associating IL17RE and cutaneous candidiasis

IL17RE [ENSP00000373325]

Interleukin 17 receptor E; Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors.

Synonyms:  IL17RE,  IL17REp,  hIL17RE,  A6NL85,  C9J1R2 ...

Linkouts:  STRING  Pharos  UniProt