Literature associating CD274 and secondary progressive multiple sclerosis
Programmed cell death 1 ligand 1; Involved in the costimulatory signal, essential for T- cell proliferation and production of IL10 and IFNG, in an IL2- dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production; Belongs to the immunoglobulin superfamily. BTN/MOG family.
Synonyms: CD274, CD274p, hCD274, Q9NZQ7, B7H1 ...