DISEASES

Disease-gene associations mined from literature

Literature associating MYBBP1A and cerebrovascular benign neoplasm

MYBBP1A [ENSP00000370968]

MYB binding protein (P160) 1a; May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter; Armadillo-like helical domain containing

Synonyms:  MYBBP1A,  MYBBP1Ap,  hMYBBP1A,  Q9BQG0,  P160 ...

Linkouts:  STRING  Pharos  UniProt  OMIM