Literature associating IL33 and chronic congestive splenomegaly
IL33 [ENSP00000370842]
Nuclear factor from high endothelial venules; Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury; Interleukins
Synonyms: IL33, IL33p, hIL33, O95760, C9orf26 ...