DISEASES

Disease-gene associations mined from literature

Literature associating GLDC and glycine encephalopathy

GLDC [ENSP00000370737]

Glycine dehydrogenase (decarboxylating), mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GCSH).

Synonyms:  GLDC,  P23378,  GCSP,  P23378p,  hP23378 ...

Linkouts:  STRING  Pharos  UniProt  OMIM