DISEASES

Disease-gene associations mined from literature

Literature associating AKR1C1 and cloacal exstrophy

AKR1C1 [ENSP00000370254]

High-affinity hepatic bile acid-binding protein; Converts progesterone to its inactive form, 20-alpha- dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation; Belongs to the aldo/keto reductase family.

Synonyms:  AKR1C1,  AKR1C1p,  hAKR1C1,  A6NHU4,  Q04828 ...

Linkouts:  STRING  Pharos  UniProt  OMIM