Literature associating AKR1C1 and ischemic bone disease
High-affinity hepatic bile acid-binding protein; Converts progesterone to its inactive form, 20-alpha- dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation; Belongs to the aldo/keto reductase family.
Synonyms: AKR1C1, AKR1C1p, hAKR1C1, A6NHU4, Q04828 ...