DISEASES

Disease-gene associations mined from literature

Literature associating NKX3-1 and rete testis adenocarcinoma

NKX3-1 [ENSP00000370253]

Homeobox protein NK-3 homolog A; Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells; Belongs to the NK-3 homeobox family.

Synonyms:  NKX3-1,  Q99801,  NKX3.1,  NKX3A,  Q99801p ...

Linkouts:  STRING  Pharos  UniProt