DISEASES

Disease-gene associations mined from literature

Literature associating AKR1C2 and parasitic protozoa infectious disease

AKR1C2 [ENSP00000370129]

Dihydrodiol dehydrogenase/bile acid-binding protein; Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha- DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.

Synonyms:  AKR1C2,  AKR1C2p,  hAKR1C2,  B4DK69,  P52895 ...

Linkouts:  STRING  Pharos  UniProt  OMIM