DISEASES

Disease-gene associations mined from literature

Literature associating TLR7 and toxic pneumonitis

TLR7 [ENSP00000370034]

Toll-like receptor 7; Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Synonyms:  TLR7,  TLR7p,  hTLR7,  B2R9N9,  Q9NYK1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM