DISEASES

Disease-gene associations mined from literature

Literature associating PIR and conversion disorder

PIR [ENSP00000369786]

Probable quercetin 2,3-dioxygenase PIR; Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro); Belongs to the pirin family.

Synonyms:  PIR,  A0A024RBX6,  O00625,  PIR-001,  PIR-002 ...

Linkouts:  STRING  Pharos  UniProt