DISEASES

Disease-gene associations mined from literature

Literature associating CHD3 and CHARGE syndrome

CHD3 [ENSP00000369716]

Chromodomain helicase DNA binding protein 3; Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity; Belongs to the SNF2/RAD54 helicase family.

Synonyms:  CHD3,  CHD3p,  hCHD3,  H7C0J3,  H7C3H7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM