DISEASES

Disease-gene associations mined from literature

Literature associating TRIM22 and rubella

TRIM22 [ENSP00000369299]

RING-type E3 ubiquitin transferase TRIM22; Interferon-induced antiviral protein involved in cell innate immunity. The antiviral activity could in part be mediated by TRIM22-dependent ubiquitination of viral proteins. Plays a role in restricting the replication of HIV-1, encephalomyocarditis virus (EMCV) and hepatitis B virus (HBV). Acts as a transcriptional repressor of HBV core promoter. May have E3 ubiquitin-protein ligase activity; Minor histocompatibility antigens

Synonyms:  TRIM22,  TRIM22p,  hTRIM22,  C9J060,  C9JIU5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM