Literature associating TRPC4 and T cell and NK cell immunodeficiency
Transient receptor potential cation channel, subfamily C, member 4; Form a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Mediates cation entry, with an enhanced permeability to barium over calcium. May also be activated by intracellular calcium store depletion; Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.
Synonyms: TRPC4, TRPC4p, hTRPC4, Q3MHB9, Q9UBN4 ...