DISEASES

Disease-gene associations mined from literature

Literature associating TRPC4 and photosensitive epilepsy

TRPC4 [ENSP00000369027]

Transient receptor potential cation channel, subfamily C, member 4; Form a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Mediates cation entry, with an enhanced permeability to barium over calcium. May also be activated by intracellular calcium store depletion; Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

Synonyms:  TRPC4,  TRPC4p,  hTRPC4,  Q3MHB9,  Q9UBN4 ...

Linkouts:  STRING  Pharos  UniProt