Disease-gene associations mined from literature

Literature associating EDN1 and renovascular hypertension

EDN1 [ENSP00000368683]

Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells . ; Belongs to the endothelin/sarafotoxin family.

Synonyms:  EDN1,  EDN1p,  hEDN1,  P05305,  Q6FH53 ...

Linkouts:  STRING  Pharos  UniProt  OMIM