Literature associating EDN1 and renovascular hypertension
Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells . ; Belongs to the endothelin/sarafotoxin family.
Synonyms: EDN1, EDN1p, hEDN1, P05305, Q6FH53 ...