Literature associating IL1RAPL1 and syndromic X-linked intellectual disability
Three immunoglobulin domain-containing IL-1 receptor-related 2; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity); Belongs to the interleukin-1 receptor family.
Synonyms: IL1RAPL1, Q7Z2H0, Q9NZN1, X5DNQ7, OPHN4 ...