Disease-gene associations mined from literature

Literature associating NR0B1 and IMAGe syndrome

NR0B1 [ENSP00000368253]

DSS-AHC critical region on the X chromosome protein 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity); Belongs to the nuclear hormone receptor family. NR0 subfamily.

Synonyms:  NR0B1,  NR0B1p,  hNR0B1,  A6NNU8,  F1D8P4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM