Literature associating CYBB and toxic myocarditis
Superoxide-generating NADPH oxidase heavy chain subunit; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
Synonyms: CYBB, F5GWU5, G8Z8Y8, P04839, F5GWU5p ...