Literature associating ITM2B and ITM2B-related cerebral amyloid angiopathy 2
Integral membrane protein 2B; Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites; Belongs to the ITM2 family.
Synonyms: ITM2B, ITM2Bp, hITM2B, Q5W0A2, Q9Y287 ...