DISEASES

Disease-gene associations mined from literature

Literature associating MMEL1 and primary biliary cholangitis

MMEL1 [ENSP00000367668]

Membrane metallo-endopeptidase-like 1; Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond (By similarity); Belongs to the peptidase M13 family.

Synonyms:  MMEL1,  MMEL1p,  hMMEL1,  J3KRD2,  Q495T6 ...

Linkouts:  STRING  Pharos  UniProt