Literature associating EXT1 and Maffucci syndrome
Putative tumor suppressor protein EXT1; Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan; Exostosin glycosyltransferase family
Synonyms: EXT1, EXT1p, hEXT1, D7RTA7, F8WF54 ...