Literature associating HIST1H4B and familial hyperinsulinemic hypoglycemia 1
HIST1H4B [ENSP00000366974]
Histone cluster 1, H4b; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms: HIST1H4B, 121504, 1ZKK, 2BQZ, 2IG0 ...