Literature associating NKX2-2 and extraskeletal myxoid chondrosarcoma
Homeobox protein NK-2 homolog B; Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity); Belongs to the NK-2 homeobox family.
Synonyms: NKX2-2, O95096, NKX2.2, NKX2B, O95096p ...