Disease-gene associations mined from literature

Literature associating NKX2-2 and oligodendroglioma

NKX2-2 [ENSP00000366347]

Homeobox protein NK-2 homolog B; Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity); Belongs to the NK-2 homeobox family.

Synonyms:  NKX2-2,  O95096,  NKX2.2,  NKX2B,  O95096p ...

Linkouts:  STRING  Pharos  UniProt