DISEASES

Disease-gene associations mined from literature

Literature associating THBD and eclampsia

THBD [ENSP00000366307]

Thrombomodulin; Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated; C-type lectin domain containing

Synonyms:  THBD,  P07204,  P07204p,  hP07204,  THRM ...

Linkouts:  STRING  Pharos  UniProt  OMIM