Disease-gene associations mined from literature

Literature associating RILPL1 and drug-induced mental disorder

RILPL1 [ENSP00000366070]

Rab interacting lysosomal protein-like 1; Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution; Belongs to the RILPL family.

Synonyms:  RILPL1,  RILPL1p,  hRILPL1,  F5H6W5,  G8JLD1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM