DISEASES

Disease-gene associations mined from literature

Literature associating WAS and neurodegeneration with brain iron accumulation 6

WAS [ENSP00000365891]

Wiskott-Aldrich syndrome protein; Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria; Wiskott-Aldrich Syndrome protein family

Synonyms:  WAS,  A0A024QYX8,  C9J3B7,  P42768,  WAS-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM