Literature associating WAS and neurodegeneration with brain iron accumulation 6
Wiskott-Aldrich syndrome protein; Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria; Wiskott-Aldrich Syndrome protein family
Synonyms: WAS, A0A024QYX8, C9J3B7, P42768, WAS-001 ...