Literature associating GATA1 and essential thrombocythemia
GATA binding protein 1 (globin transcription factor 1); Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS; GATA zinc finger domain containing
Synonyms: GATA1, GATA1p, hGATA1, B7WNQ9, GATA1-001 ...