DISEASES

Disease-gene associations mined from literature

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Literature associating MTHFR and nutritional deficiency disease

MTHFR [ENSP00000365777]

Methylenetetrahydrofolate reductase (NAD(P)H); Catalyzes the conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co- substrate for homocysteine remethylation to methionine.

Synonyms:  MTHFR,  F6XU28,  L7P8G6,  P42898,  Q5SNW5 ...

Linkouts:  STRING  Pharos  UniProt

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.