DISEASES

Disease-gene associations mined from literature

Literature associating NPPA and heart disease

NPPA [ENSP00000365663]

Cardiodilatin-related peptide; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3; Belongs to the natriuretic peptide family.

Synonyms:  NPPA,  B0ZBE8,  P01160,  ANP,  B0ZBE8p ...

Linkouts:  STRING  Pharos  UniProt  OMIM