DISEASES

Disease-gene associations mined from literature

Literature associating NPPB and restrictive cardiomyopathy

NPPB [ENSP00000365651]

Gamma-brain natriuretic peptide; Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3; Belongs to the natriuretic peptide family.

Synonyms:  NPPB,  P16860,  P16860p,  hP16860,  1YK1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM