Literature associating AIF1 and autoimmune optic neuritis
Ionized calcium-binding adapter molecule 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation; EF-hand domain containing
Synonyms: AIF1, AIF1p, hAIF1, IBA1, 199 ...