Disease-gene associations mined from literature

Literature associating NUDT10 and autoimmune polyendocrine syndrome

NUDT10 [ENSP00000365174]

Nudix (nucleoside diphosphate linked moiety X)-type motif 10; Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate; Nudix hydrolase family

Synonyms:  NUDT10,  NUDT10p,  hNUDT10,  Q8NFP7,  APS2 ...

Linkouts:  STRING  Pharos  UniProt