DISEASES

Disease-gene associations mined from literature

Literature associating TNFSF13B and neuromyelitis optica

TNFSF13B [ENSP00000365048]

Tumor necrosis factor (ligand) superfamily, member 13b; Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response; CD molecules

Synonyms:  TNFSF13B,  Q9Y275,  TNFSF13B-001,  TNFSF13B-002,  TNFSF13B-003 ...

Linkouts:  STRING  Pharos  UniProt  OMIM