DISEASES

Disease-gene associations mined from literature

Literature associating FBXO42 and hereditary desmoid disease

FBXO42 [ENSP00000364742]

Just one F-box and Kelch domain-containing protein; Substrate-recognition component of some SCF (SKP1-CUL1- F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation; F-boxes other

Synonyms:  FBXO42,  FBXO42p,  hFBXO42,  A0A024QZB0,  FBXO42-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM