DISEASES

Disease-gene associations mined from literature

Literature associating F7 and hemorrhagic disease

F7 [ENSP00000364731]

Coagulation factor VII (serum prothrombin conversion accelerator); Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium; Gla domain containing

Synonyms:  F7,  F7p,  hF7,  A3RKG7,  E9PH36 ...

Linkouts:  STRING  Pharos  UniProt  OMIM