Literature associating XPA and skin carcinoma
Xeroderma pigmentosum group A-complementing protein; Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation; Belongs to the XPA family.
Synonyms: XPA, F2Z2T2, P23025, F2Z2T2p, hF2Z2T2 ...