DISEASES

Disease-gene associations mined from literature

Literature associating PSMB9 and Graves' disease

PSMB9 [ENSP00000363993]

Proteasome (prosome, macropain) subunit, beta type, 9; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues.

Synonyms:  PSMB9,  PSMB9p,  hPSMB9,  P28065,  LMP2 ...

Linkouts:  STRING  Pharos  UniProt